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NAD+ and glutathione support each other through interconnected biochemical pathways, with NAD+ metabolism producing NADPH that regenerates active glutathione from its oxidized form

Such reductions in blood pressure seem comparable to those reported with currently used classes of blood pressure-lowering medications (average reduction, -9.1 mm Hg for SBP and -5.5 mm Hg for DBP) (108)

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However, they also raise challenges regarding pharmacological interventions targeting the WNT pathway for ASD treatment, as a careful balance of both WNT antagonists and agonists would be needed